Molecular Formula | C27H32O15 |
Molar Mass | 596.53 |
Density | 1.77 |
Melting Point | 161-190°C |
Boling Point | 956.9±65.0 °C(Predicted) |
Specific Rotation(α) | -62 (c, 1.4 in MeOH) |
Flash Point | 317°C |
Solubility | DMSO : 125 mg/mL (209.55 mM; Need ultrasonic) |
Vapor Presure | 0mmHg at 25°C |
Appearance | White amorphous powder |
Color | Dark Beige to Very Dark Beige |
BRN | 1304401 |
pKa | 7.15±0.40(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.727 |
MDL | MFCD00017472 |
Physical and Chemical Properties | Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, from lemon, citrus fruit trees. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29389090 |
Reference Show more | 1. Shi Ying, Liu Yuan, Chen Jiajing, et al. Effects of Huanglong Disease Infection on Flavonoids and Volatile Substances in Citrus chinensis [J]. Journal of Huazhong Agricultural University, 2020, v.39(01):30-39. 2. Zhang Xue, Zhu Zihao, Zhang Bo, Guo Xingjie. Separation of Five Flavanone Glycoside Isomers by Cellulose Bonded Chiral Stationary Phase [J]. Journal of Shenyang Pharmaceutical University, 2020,37(10):903-907. 3. Yulong Zhang, Zi Liu, Lina Zou, Baoxian Ye,A new voltammetry sensor platform for eriocitrin based on CoS2-MoS2-PDDA-GR nanocomposite,Talanta,Volume 189,2018,Pages 345-352,ISSN 0039-9140,https://doi.org/10.1016/j.talanta. 2018.07.004. 4. [IF=6.057] Yulong Zhang et al."A new voltammetry sensor platform for eriocitrin based on CoS2-MoS2-PDDA-GR nanocomposite."Talanta. 2018 Nov;189:345 5. [IF=7.514] Jing Zhao et al."A sensitive and practical ELISA for analyzing naringenin in pummelo and herb samples."Food Chem. 2021 Nov;362:130223 6. [IF=6.543] Wang Yue et al."Polymethoxyflavones in Citrus Regulate Lipopolysaccharide-Induced Oscillating Decay of Circadian Rhythm Genes by Inhibiting Nlrp3 Expression."Oxid Med Cell Longev. 2021;2021:8419415 7. [IF=5.279] Jiajing Chen et al."Primary Bitter Taste of Citrus is Linked to a Functional Allele of the 1,2-Rhamnosyltransferase Gene Originating from Citrus grandis."J Agr Food Chem. 2021;69(34):9869-9882 8. [IF=4.952] Guanyi Peng et al."Combined microwave and enzymatic treatment improve the release of insoluble bound phenolic compounds from the grapefruit peel insoluble dietary fiber."Lwt Food Sci Technol. 2021 Sep;149:111905 9. [IF=4.759] Miaoduo Deng et al."Preparation of a hydroxypropyl-β-cyclodextrin functionalized monolithic column by one-pot sequential reaction and its application for capillary electrochromatographic enantiomer separation."J Chromatogr A. 2019 Oct;1603:269 10. [IF=4.411] Liuyi Yu et al."Systematic Detection and Identification of Bioactive Ingredients from Citrus aurantium L. var. amara Using HPLC-Q-TOF-MS Combined with a Screening Method."Molecules. 2020 Jan;25(2):357 11. [IF=3.935] Junmao Li et al."Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering."J Pharmaceut Biomed. 2022 Mar;211:114621 |
Plant source: | Fructus Aurantii Immaturus |
biological activity | Eriocitrin is a flavonoid compound isolated from lemon, which is a powerful antioxidant. Eriocitrin inhibit the proliferation of hepatoma cells by up-regulating p53,cyclin A,cyclin D3 and CDK6 to arrest the S-phase cell cycle. Eriocitrin trigger apoptosis by activating the intrinsic signaling pathways involved in mitochondria. |
use | for content determination/identification/pharmacological experiments and other pharmacological effects: it has strong antioxidant effect and is long used as an antioxidant for beverages, foods and wines. Holy grass glycoside can inhibit oxidative stress injury induced by acute liver exercise in rats, and can reduce blood lipid. Its antioxidant capacity is stronger than hesperidin and naringin. The saccharin can inhibit the oxidative stress injury induced by acute exercise in the liver of rats, and can reduce blood lipids. The antioxidant capacity of saccharin is stronger than that of hesperidin and naringin. |